Histopathology

Histopathology

SR NOTESTTEST COMPONENTSMETHODSPECIMEN/TRANSPORTTATCLINICAL APPLICATIONS
1Special stainsPAS stain-for fungal elements
ZN stain for acid fast bacilli
ManualFormalin fixed tissue48 to 72 hrs, may be longer if longer bone decalcification requiredFor detection of infective pathology
2Immunohistochemistry studyA) Undifferentiated malignant tumor (Basic localising Panel)*
· LCA
· Pan CK
· S100
· Vimentin
* Additional markers will be put after confirmation of initial lineage.
B) Metastatic adenocarcinoma of unknown primary
· CK7
· CK20
· PSA
· CA125
· GCDFP-15
· Hepar 1
· CDX2
· TTF1
· NAPSIN
· CK19
C) Metastatic squamoid carcinoma with unknown primary
· CK20
· CK7
· CK HMW
· EBV
· CD5
· P63
· P16
· CK 5/6
Leica BondMax fully automated IHC machineFormalin fixed tissue3-4 days
May very if prolonged decalcificaiton required
For definitive diagnosis suspected on routine histopathology stain.